It may surprise some of you to find that you are far more familiar with such a seemingly complicated medical term than you may think upon first glance. That's right, some of you who are reading this have experienced pain in your hand or wrist on a daily basis. Stop thinking it's just some little pain or that you must have just tweaked your wrist and that it will get better soon. De Quervain's tenosynovitis isn't something that will cause permanent damage, but it's quite painful. So, be smart about that pain and have it checked out by a doctor.