The Medicinal uses of the lorazepam are so many and so important. It has the strong sedative as well as hypnotic effects and it is an appropriate choice when the treatment of the insomnia is concerned because of duration of effect of the single dose in clinic. And it is particularly very effective in the treatment of severe anxiety. The duration in which its effect is start showing is comparatively very short. The rebound anxiety as well as rebound insomnia, or as whole withdrawal symptoms, may be able to occur after administratinglorazepam for seven days. It may be given to the patients who are receiving mechanical ventilation.