The only difference is that the 10% concentration will only produce an effect irritating your skin 4 times more. Azelaic acid. Although not as frequently used by men as compared with benzoyl peroxide, azelaic acid is still one of the favourites against a household adult acne. As a benzoyl peroxide, azelaic acid helps your adult acne treatment in three ways. It kills bacteria, reduce inflammation and skin open up your pores. Like any other acne treatment, azelaic acid also has a skin irritation effects. So, for those with mild or moderate acne, topical cream could work for you. For severe acne cases, is not recommended to use topical creams.