Oprah colon cleanse mainly consist of acai berry extracts. These amazing supplements do not cost much and do not carry any kind of side effect also. These supplements clear out the waste materials and toxicity that has sustained in your body for so many years. Another use of having these supplements is that they have great weight loss properties and within few months you can lose pounds by the regular consumption of these supplements. Acai berry consists of omega 3 which is widely known for its colon cleanses action on a human body. It also keeps he skin fresh and smooth.