The best acne treatment is obviously the one that works best for you. There are many different treatment options and not all will work for each person. A lot depends on the severity of the acne. Those with a light case of acne may find the best acne treatment is washing with over-the-counter preparations that contain benzoyl peroxide. For those with severe acne the best acne treatment may be the oral medications and topical creams that can only be prescribed by a dermatologist. No matter what type of treatment you use follow the directions exactly for the best results.